Sarah J. Wheelan, MD, PhD
Assistant Professor, Oncology Biostatistics
The Johns Hopkins University School of Medicine
550 North Broadway, Suite 1103
Baltimore, MD 21205
Tel 410-502-7754
Fax 410-955-0859
swheelan AT-SIGN jhmi.edu

Original Research Articles

An W, Han JS, Wheelan SJ, Davis ES, Coombes CE, Ye P, Triplett C, Boeke JD. Active retrotransposition by a synthetic L1 element in Mice. Proceedings of the National Academy of Sciences, 2006 Dec 5;103(49):18662-7 PubMed

Wheelan SJ, Scheifele LZ, Martinez-Murillo F, Irizarry RA, Boeke JD. The Transposon site Insertion Profiling Chip (TIP-chip). Proceedings of the National Academy of Sciences, 2006 Nov 21;103(47):17632-7. PubMed

Wheelan SJ, Marti­nez-Murillo F, Irizarry RA, Boeke JD. Stacking the deck: double-tiled DNA microarrays. NatureMethods, 2006 Nov;3(11):903-7 PubMed

Richardson SM, Wheelan SJ, Yarrington RM, Boeke JD. GeneDesign: Rapid, Automated Design of Multikilobase Synthetic Genes. Genome Research 2006 Feb 15;[Epub ahead of print]. PubMed

Wheelan SJ, Aizawa Y, Han JS, Boeke JD. Gene-breaking: a new paradigm for human retrotransposon-mediated gene evolution. Genome Research 2005 Aug;15(8):1073-8. PubMed

Marth G, Schuler G, Yeh R, Davenport R, Agarwala R, Church D, Wheelan S, Baker J, Ward M, Kholodov M, Phan L, Czabarka E, Murvai J, Cutler D, Wooding S, Rogers A, Chakravarti A, Harpending HC, Kwok PY, Sherry ST. Sequence variations in the public human genome data reflect a bottlenecked population history. PNAS 2003 Jan 7;100(1):376-81. PubMed

Wheelan SJ, Church DM, Ostell JM. Spidey &mdash a tool for mRNA-to-genomic alignments. Genome Research 2001 Nov; 11:1952-1957. PubMed

Onyango P, Miller W, Lehoczky J, Leung CT, Birren B, Wheelan S, Dewar K, Feinberg AP. Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain. Genome Research 2000 Nov;10(11):1697-710. PubMed

Wheelan SJ, Marchler-Bauer A, Bryant SH. Domain size distributions can predict domain boundaries. Bioinformatics 2000 Jul;16(7):613-8. PubMed

Wheelan SJ, Boguski MS, Duret L, Makalowski W. Human and nematode orthologs &mdash lessons from the analysis of 1800 human genes and the proteome of Caenorhabditis elegans. Gene 1999 Sep 30;238(1):163-70. PubMed


Book Chapters

Boeke JD, An W, Dai L, Davis ES, Han JS, O'Donnell KA, Scheifele LZ, Wheelan SJ Retrotransposons &mdash Natural and Synthetic. In Retrotransposition, Diversity and the Brain. Fred Gage (Editor), Yves Christen (Editor) First Edition, 2007.

Kans J, Wheelan SJ, and Ostell J. The NCBI Data Model. In Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. Andreas Baxevanis(Editor), B.F.Francis Ouellette (Editor) 2nd Edition, 2001.


Editorials

Wheelan SJ, Martinez-Murillo F, Boeke JD. The incredible shrinking world of DNA microarrays. Molecular BioSystems 2008 Jul; 4(7):726-32. Epub 2008 Apr 17. PubMed

Wheelan S, Makalowski W. Genome research: the second decade. A report on the XI Cold Spring Harbor Laboratory Meeting on Genome Mapping and Sequencing, May 13-17, 1998, Cold Spring Harbor, NY. Comput Chem. 2000 Jan;24(1):125-7. PubMed

Wheelan SJ, Boguski MS. Late-night thoughts on the sequence annotation problem. Genome Research 1998 Mar;8(3):168-9. PubMed

	University of Colorado at Boulder 1995: Bachelor of Arts, GPA 4.0, three majors   Summa cum laude Molecular, Cellular and Developmental Biology   Summa cum laude Mathematics   Biochemistry   . . . minor in chemistry
	The Johns Hopkins University School of Medicine 2003: MD 2003: PhD, Human Genetics   Thesis: The Alignment Manager   Advisors: Dr. Jim Ostell, NCBI, Dr. Tom Kelly, Hopkins
	2004-2006: Postdoctoral Fellowship, Jef Boeke, Hopkins/HiT center
	2006-present: Assistant Professor, Oncology Biostatistics

Bailey, Papillon

Guinness, Doberman

Brian, my husband and a graphic designer, shares my love of the great outdoors (as I am a Wyomingite/Coloradan at heart) and of museums, music, and food. Hiking with the dogs is one of our favorite pastimes. I also enjoy crocheting and most of my friends have received baby blankets from us. Brian enjoys gourmet cooking, and I enjoy gourmet baking, so we need to get the dogs out for walks quite often.